Weight Loss Specialist

Dominic Sorrentino, PA-C, ABAAHP -  - Anti-Aging

Affinity Wellness 4 Life

Dominic Sorrentino, PA-C, ABAAHP

Anti-Aging & Medical Spa located in Lakewood Ranch, FL

Weight loss is no easy feat, which is why most adults in the United States are overweight or obese. Unwanted weight gain might result from an untreated medical condition, such as a hormone imbalance. At Affinity Wellness 4 Life in Bradenton, Florida, Dominic Sorrentino Jr., PA-C, and his experienced weight loss team offer nutraceuticals, B12 injections, and appetite suppressants to simplify weight loss. Schedule a consultation with Affinity Wellness 4 Life by phone or online today.

Weight Loss Q & A

What is medical weight loss?

Medical weight loss is a weight loss program Sorrentino and his team offer to increase your chance of reaching your goal weight and maintaining it for life. 

They diagnose and treat medical conditions responsible for failed weight loss, such as a thyroid disorder or other hormone imbalances, and provide the structure and accountability needed to help you succeed.

What are the risk factors for overweight and obesity?

There are numerous factors that increase your risk of becoming overweight or obese. Examples include:

  • Testosterone, estrogen, or thyroid imbalances
  • Increases in appetite
  • Poor dietary habits
  • Insufficient sleep
  • Chronic stress
  • Fatigue
  • Insufficient physical activity
  • Depression or anxiety
  • Emotional trauma

Sorrentino and his team find the root cause of overweight or obesity to create a personalized weight loss plan that best matches your unique needs.

What should I expect during my appointment?

During medical weight loss appointments, practitioners at Affinity Wellness 4 Life review your medical history, weigh you, and check your vitals. They utilize blood tests to evaluate hormone, vitamin, and mineral levels and diagnose health conditions.

They analyze your current diet and exercise patterns to create a personalized weight loss treatment plan, which might include one or more of the following:

B12/mic injections

B12 plus methionine injections facilitate weight loss by giving you a boost of energy, increasing hydration, accelerating metabolism, and enhancing fat breakdown.


Your practitioner might recommend taking nutraceuticals, such as detoxification formulas or protein shakes, to detoxify your body, give you a boost of energy, control your appetite, and help you maintain lean body mass during periods of energy restriction.

Appetite suppressants/medications

Taking medications or appetite suppressants controls your appetite, making it easier to eat fewer calories during weight loss without feeling hungry.

Exercise/diet programs

Sorrentino and his experienced weight loss team develop a personalized diet and exercise program based on your unique needs. They create menu plans and fat-burning workouts, so you know exactly what to eat and how often to exercise to achieve your goal weight and dream body.

Don’t give up on losing weight, as medical weight loss significantly increases your chance of success. Schedule a consultation with the medical team at Affinity Wellness 4 Life by phone or online today.

Programs Offered

1. 40-day Kisspeptin weight loss plan

2. 8 week Lipovitol/ B12 weight loss program

3. 8 Week all Inclusive Medical Weight Loss Program - $888.88

Affinity Wellness 4 Life ALL NEW!

8 Week Lipovitol Weight Loss Program

Affinity Wellness 4 Life is pleased to introduce our NEW 8 Week Lipovitol Weight Loss Program! Our medically trained staff will be dedicated to helping you achieve weight / body fat reduction!  This program is highly effective in helping achieve desired body image through education of proper diet, supplementation and exercise management!!

Our 8 week program will take you step by step through a journey of weight reduction and total body wellness.

The 8 week program includes:

- Comprehensive Medical History and Physical Exam
- Full Dietary Planning
- Detoxification Supplements, Meal Replacement Protein Shakes and Metabolic Stimulators
- Exercise Advice
- Weekly Weight Checks and Body Measurement Analysis
- Weekly Lipovitol / b12 Weight Loss Injections
- Prescription appetite suppressants

Laboratory Blood Work with Hormone and Vitamin Analysis (optional at addl costs)

Call today to set up an appointment and be on your way to a thinner healthier you!!

Live Younger and Lighter...Longer...Affinity

4. Kisspeptin Medical Weight Loss Program - $477.77

Kisspeptin Diet For Weight Loss: An Effective Alternative to HCG Injections?

As we have explored in multiple reports, the FDA has placed burdensome limitations on compounding pharmacies’ ability to produce human chorionic gonadotropin (HCG) – one of the main supplements we have successfully used at HCG Diet Miami to help thousands of patients lose weight.

Given these developments, we’ve had to look elsewhere to achieve the same weight loss results using alternative treatments. Through extensive research, we’ve discovered that the kisspeptin diet delivers impressive weight loss results similar to HCG – in addition to other notable health benefits.

Let’s get into the details regarding kisspeptin weight loss and why we are excited to introduce it to our patients at Affinity Wellness 4 Life!

What Is Kisspeptin and How Does It Work?

Here are the highlights on kisspeptin:

  • A polypeptide hormone produced in the hypothalamus, a region of the midbrain
  • In humans, the KISS1 gene encodes the hormone
  • The number following the name indicates the number of amino acids in the protein – for example, kisspeptin-10, the most effective version for raising LH levels and stimulating weight loss, is a sequence of 10 amino acids
  • Standard dose of .1-.2mL per injection, 2-3 times weekly to daily may be suggested

Some practitioners refer to kisspeptin as its original name, “metastin,” for its ability to suppress metastization (cancer growth). (See later section for the anti-aging health benefits of kisspeptin in addition to weight loss.)

Let’s get into how kisspeptin turbo-charges weight loss and why it’s the ideal alternative to FDA-banned HCG.

How Does HCG Work For Weight Loss and Why Is Kisspeptin the Best Alternative?

In the specific context of weight loss, kisspeptin works within the same hormone feedback loop that HCG acts on — the critical hypothalamic-pituitary-gonadal (HPG) axis –to promote weight loss in two specific ways that we will explore in detail here:

  • Boosting luteinizing hormone (LH) levels
  • Boosting adiponectin levels

HPG and the HPG Axis

Kisspeptin acts on the HPG axis according to the following sequence:

  • Kisspeptin triggers the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus
  • GnRH travels to the pituitary gland where it triggers the release of two hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This pair of hormones is primarily involved in maintaining reproductive health but is also heavily implicated in metabolism and weight management
  • LH and FSH trigger the release of sex hormones (primarily estradiol in women and testosterone in men)
  • The loop comes full circle with the sex hormones regulating the release of leptin, adiponectin, and other hormones in the brain responsible for metabolism and fat burning

The chart below illustrates the flow of the HPG axis hormone feedback loop:








Kisspeptin acts powerfully on this axis. Via ScienceDirect:

“Comparison of the releasing effects of kisspeptins with those of other neuropeptides and neurotransmitters indicates that kisspeptins are probably the most potent stimulator of the gonadotropic axis known so far.”








Kisspeptin Stimulates As High as 60 Times Greater LH Release

Research has demonstrated kisspeptin’s remarkable capacity to achieve exponential gains in LH secretion, particularly in combination with fasting (a protocol we already use in the HCG diet):

“In fed animals, both prepubertal female and male rats demonstrated a 9 to 10 fold increase in LH concentrations in serum 15 minutes after i.c.v. injection of kisspeptin. In contrast, fasted rats demonstrated a much greater 50 to 60 fold increase in LH release. Moreover, the kisspeptin-stimulated release of GnRH from hypothalamic explants collected from rats that were fasted for 72 h was greater than that from hypothalamic explants collected from ad libitum fed rats.”

In particular, kisspeptin-10, which consists of a chain of 10 amino acids (pared down from the 53-amino-acid chain in kisspeptin’s original form), generates the greatest LH gains. Via ScienceDirect:

“Proteolytic cleavage of the primary product of the KiSS1 gene, a 53-amino-acid peptide known as kisspeptin or metastin, generates the decapeptide kisspeptin-10, which is a potent stimulator of LH release.”

The chart below indicates the beneficial impacts of therapeutic kisspeptin administration on LH:

Source: InTechOpen

Kisspeptin Stimulates Higher Adiponectin Levels For Weight Loss

In addition to its beneficial impact on LH levels, kisspeptin also mimics the effects of HCG by boosting adiponectin levels, another important weight loss mechanism in the HCG diet:

Kisspeptin administration significantly increased (p<0.05) mean plasma adiponectin levels under fed and 24-h fasting conditions as compared to pretreatment or vehicle-treatment levels….Thus, the present study demonstrated a stimulatory effect of peripheral kisspeptin administration on the plasma adiponectin levels under fed and 24-h fasting conditions in the adult male rhesus monkey. These findings, therefore, assign a novel role to kisspeptin, a regulator of adipocyte function in higher primates.”

Adiponectin, in turn, supercharges the breakdown of fatty acids and regulates blood sugar (glucose) levels:

“Studies have shown that adiponectin also helps to manage weight by controlling the levels of glucose within the body and by breaking down fatty acids. Therefore, activating adiponectin and increasing the levels in the blood can help with the management of weight and weight-related disorders.”

photo of Affinity Wellness 4 Life

“A new study suggests that the hormone adiponectin, which is found in fat tissue, can cause weight loss by boosting metabolism without affecting appetite. Researchers say that the finding may lead to better treatments for obesity and other metabolic disorders, such as diabetes.”

The bottom line: if accelerating fat metabolism without the hunger associated with “normal” dieting sounds attractive, kisspeptin hormone therapy for higher adiponectin levels might be right for you.

What Other Anti-Aging Benefits Besides Weight Loss Does Kisspeptin Offer?

The research into the clinical significance of kisspeptin is still in its infancy, but anti-aging experts have already taken an enormous interest in this potentially transformative peptide hormone.

The research-backed benefits that kisspeptin offers to those who receive it through therapy include:


Benefits of Kisspeptin* during Weight Loss

On-going research is showing that Kisspeptin | HCG * combined with a Medically Supervised Very Low Calorie Diet (VLCD) can help:

  • Increased loss of Fat during weight loss.
  • Decreased Irritability & weakness during weight loss.
  • Improvement in Sleep.
  • Clinical Research.
  • Utility of an Oral Presentation of Kisspeptin | HCG * (human Choriogonadotropin) for the Management of Obesity. A Double-Blind Study.
  • Effect of human chorionic gonadotrophin on weight loss, hunger, and feeling of well-being.

** disclaimer:  Kisspeptin / HCG Disclaimer* : Kispeptin and HCG work on the same or at least similar pathways functionally . However, in the recent turn of events hcg is no longer available or compounded by the compounding pharmacies anymore for the medical weight loss support programs.

Affinity Wellness 4 Life 40-day Kisspeptin weight loss Plan includes:

  • Full instructional Kisspeptin consultation (30-40 min)
  • 40-day supply injectable Kisspeptin peptide
  • Weekly weight checks and maintenance checks
  • Multivitamins
  • Detoxification support formula
  • Post period maintenance and exercise planning
  • Laboratory blood work and hormonal assessment post-period (optional with addl costs)
  • Weekly lipovitol / b12 fat burn shots and appetite suppressants (optional)

Call Today to book your 40- day Kisspeptin rapid weight-reduction plan!